LEGEMA Lab
INISA — Instituto de Investigaciones en Salud
Producción científica

Publicaciones

25 publicaciónes científicas del laboratorio.

Destacadas
Anthropogenic imprint on riverine plasmidome diversity and proliferation of antibiotic resistance genes following pollution and urbanization

Barrantes-Jiménez, K., Lejzerowicz, F., Tran, T., Calderón-Osorno, M., Rivera-Montero, L., Rodríguez-Snchez, C., Wikmark, O. G., Eiler, A., Grossart, H. P., Arias-Andrés, M., & Rojas-Jiménez, K. (2025). Anthropogenic imprint on riverine plasmidome diversity and proliferation of antibiotic resistance genes following pollution and urbanization. Water Research, 281, 123553. https://doi.org/10.1016/j.watres.2025.123553

Todas las publicaciones
2026
Antimicrobial resistance and phylogenetic diversity of Escherichia coli isolates from coastal recreational waters in Costa Rica.

Montiel-Mora JR, Rivera-Montero L, Badilla-Aguilar A, Barrantes K, Rivera-Navarro P, Chacón L. Antimicrobial resistance and phylogenetic diversity of Escherichia coli isolates from coastal recreational waters in Costa Rica. Environmental Monitoring and Assessment. 2026;198:176. https://doi.org/10.1007/s10661-026-15002-z

Insights into the riverine metaplasmidome: The role of anthropogenic factors in shaping microbial communities.

Calderón-Osorno M, Barrantes-Jiménez K, Lejzerowicz F, Arias-Andres M, Rojas-Jiménez K. Insights into the riverine metaplasmidome: The role of anthropogenic factors in shaping microbial communities. The Microbe. 2026;10:100640. https://doi.org/10.1016/j.microb.2025.100640

Applying weighted quantile sum regression to wastewater surveillance: enteric viral mixtures and diarrheal disease trends in Costa Rica.

Morales E, Rivera-Montero L, Ramos-Montalvo N, Montiel-Mora J, Mendoza-Guido B, Alfaro-Arrieta E, Rivera-Navarro P, Barrantes K, Chacón L. Applying weighted quantile sum regression to wastewater surveillance: enteric viral mixtures and diarrheal disease trends in Costa Rica. Journal of Water and Health. 2026.

Temperature-driven dynamics in prokaryotic and eukaryotic communities of an aerobic granular sludge lab-scale reactor.

Barrios-Hernandez, M. L., Solomon, T., Orias-Obando, F., Mendoza-Guido, B., & Hooijmans, C. M. (2026). Temperature-driven dynamics in prokaryotic and eukaryotic communities of an aerobic granular sludge lab-scale reactor. Science of The Total Environment, 1024, 181591. https://doi.org/10.1016/j.scitotenv.2026.181591.

Multiple exposure pathways to pesticide residues in tropical agroecosystems: A human health risk assessment in Costa Rica.

Montiel-Mora JR, Pérez-Rojas G, Brenes-Alfaro L, Rodríguez-Rodríguez CE. Multiple exposure pathways to pesticide residues in tropical agroecosystems: A human health risk assessment in Costa Rica. Environmental Monitoring and Assessment. 2026;198:47

Antimicrobial resistance in coastal waters of Latin America: current knowledge and challenges.

Montiel-Mora JR, Segura-Arroyo P, Barrantes K, Mendoza-Guido B, Chacón L. Antimicrobial resistance in coastal waters of Latin America: current knowledge and challenges. Discover Public Health. 2026;23:261.

Genome-resolved metagenomics of a neotropical wastewater treatment plant reveals community-wide metal and biocide-resistance genes and the diversity of phosphate-accumulating and denitrifying bacteria.

Mendoza-Guido B, Castro-Camacho V, Quesada-González A, Chacón L, Barrios-Hernández ML. Genome-resolved metagenomics of a neotropical wastewater treatment plant reveals community-wide metal and biocide-resistance genes and the diversity of phosphate-accumulating and denitrifying bacteria. International Biodeterioration & Biodegradation. 2026;208:106258. https://doi.org/10.1016/j.ibiod.2025.106258

2025
Draft genome sequences of four potential new species of the genus Bradyrhizobium isolated from root nodules of native legumes in Costa Rican forests.

Fernández-Vargas R, Jiménez-Alpízar S, Leandro-Arce V, Mendoza-Guido B, Rojas-Jiménez K. Draft genome sequences of four potential new species of the genus Bradyrhizobium isolated from root nodules of native legumes in Costa Rican forests. Access Microbiol. 2025;7:000990.v3. https://doi.org/10.1099/acmi.0.000990.v3

Draft genome sequence of Methylobacterium aquaticum LEGMi-203a isolated from root nodules of Pithecellobium hymenaeifolium.

Castro-Camacho V, Robles-Azor R, Rodríguez-Burdock L, Rojas-Jiménez K, Mendoza-Guido B. Draft genome sequence of Methylobacterium aquaticum LEGMi-203a isolated from root nodules of Pithecellobium hymenaeifolium. Microbiol Resour Announc. 2025. https://doi.org/10.1128/mra.00754-25

Caracterización hidrogeológica del sistema acuífero ubicado en las comunidades Isla Chica y La Trocha, cantón de Los Chiles, Alajuela

Vargas R, Alpízar R, Chacón-Jiménez L, Fuentes-Schweizer P, Barahona M. Caracterización hidrogeológica del sistema acuífero ubicado en las comunidades Isla Chica y La Trocha, cantón de Los Chiles, Alajuela. Rev Geol Am Cent. 2025;72:1-16. https://doi.org/10.15517/rgac.2025.65179

Genomic analysis of IncH plasmids reveals their role as drivers of antimicrobial resistance and adaptive traits in enterobacterales.

* Mendoza-Guido, B., Durán-Mendez, S., Barrantes, K., Rojas-Jimenez, K., & Chacón, L. (2025). Genomic analysis of IncH plasmids reveals their role as drivers of antimicrobial resistance and adaptive traits in enterobacterales. FEMS Microbiology Letters, fnaf148. https://doi.org/10.1093/femsle/fnaf148

Aplicación de tres índices de calidad del agua en un río tropical de Costa Rica: el caso del río Durazno

Montiel-Mora JR, Gómez-Ramírez EH, Irías-Mata A, Chacón-Jiménez L, Barrantes-Jiménez K, Fuentes-Schweizer P. Aplicación de tres índices de calidad del agua en un río tropical de Costa Rica: el caso del río Durazno. UNED Res J. 2025;17(1):e5921. https://doi.org/10.22458/urj.v17i1.5921

Influence of seasonality and pollution on the presence of antibiotic resistance genes and potentially pathogenic bacteria in a tropical urban river.

Barrantes-Jiménez K, Mendoza-Guido B, Morales-Mora E, Rivera-Montero L, Montiel-Mora J, Chacón-Jiménez L, Rojas-Jiménez K, Arias-Andrés M. Influence of seasonality and pollution on the presence of antibiotic resistance genes and potentially pathogenic bacteria in a tropical urban river. Antibiotics. 2025;14:798. https://doi.org/10.3390/antibiotics14080798

Comprehensive plasmidomic analysis of Helicobacter pylori reveals the potential role of plasmids in pathogenic adaptation and a novel putative toxin-antitoxin system.

Mendoza-Guido B, Romero-Carpio JD, Molina-Castro S. Comprehensive plasmidomic analysis of Helicobacter pylori reveals the potential role of plasmids in pathogenic adaptation and a novel putative toxin-antitoxin system. FEMS Microbiol Lett. 2025;372:fnaf092. https://doi.org/10.1093/femsle/fnaf092

Utilizing performance parameters in wastewater treatment plants for the implementation of wastewater-based epidemiology.

Morales-Mora E, Centeno-Mora E, Barrios-Hernández ML, Chacón L. Utilizing performance parameters in wastewater treatment plants for the implementation of wastewater-based epidemiology. In: Souabi S, et al., editors. Wastewater Treatment Plants. Water Science and Technology Library. Cham: Springer; 2025. p. 137-176. https://doi.org/10.1007/978-3-031-87461-1_8

Molecular epidemiology of aquatic environments: challenges from sampling to implementation of surveillance programs.

Mendoza-Guido B, Montiel-Mora JR, Ureña-Salazar C, Barrantes K, Chacón L. Molecular epidemiology of aquatic environments: challenges from sampling to implementation of surveillance programs. Front Public Health. 2025;13:1652535. https://doi.org/10.3389/fpubh.2025.1652535

Antibiotic resistance genes and pathobiome in a wastewater treatment plant: insights from environmental surveillance

Molina-Ospina A, Rivera-Montero L, Barrantes-Jiménez K, Montiel-Mora JR, Chacón-Jiménez L. Antibiotic resistance genes and pathobiome in a wastewater treatment plant: insights from environmental surveillance. Sci Total Environ. 2025.

Draft genome sequences of five Rhizobium spp. isolates including one potential new species from legume tropical plants in Costa Rica.

Campos-Parra D, Blanco-Picado A, Herrera-Quesada J, Mendoza-Guido B and Rojas-Jimenez K. Draft genome sequences of five Rhizobium spp. isolates including one potential new species from legume tropical plants in Costa Rica. (2025).

Novel Aeromonas hydrophila subsp. inisa with potential phage-mediated tolerance to benzalkonium chloride.

Chacón L, Mendoza-Guido B, Rodríguez-Rojas A, Rojas-Jiménez K. Novel Aeromonas hydrophila subsp. inisa with potential phage-mediated tolerance to benzalkonium chloride. Front Bacteriol. 2025;4:1709187. https://doi.org/10.3389/fbrio.2025.1709187

Assessing microbial risks of Escherichia coli: a spatial and temporal study of virulence and resistance genes in surface water in resource-limited regions.

Morales-Mora E, Rivera-Montero L, Montiel-Mora JR, Barrantes-Jiménez K, Chacón-Jiménez L. Assessing microbial risks of Escherichia coli: a spatial and temporal study of virulence and resistance genes in surface water in resource-limited regions. Sci Total Environ. 2025;958:178044.

2024
The impact of urban pollution on plasmid-mediated resistance acquisition in Enterobacteria from a tropical river

Mendoza-Guido B, Barrantes K, Rodríguez C, Rojas-Jiménez K, Arias-Andrés M. The impact of urban pollution on plasmid-mediated resistance acquisition in Enterobacteria from a tropical river. Antibiotics. 2024;13:1089.

Assessment of mathematical approaches for the estimation and comparison of efficiency in qPCR assays for a prokaryotic model.

Molina-Mora JA, Sibaja-Amador M, Rivera-Montero L, Chacón-Arguedas D, Guzmán C, García F. Assessment of mathematical approaches for the estimation and comparison of efficiency in qPCR assays for a prokaryotic model. DNA. 2024;4:189-200.